BIBLIOGRAFIA PROPOLEOS ANTIBIOTICO
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| 1: Rev Bras Enferm. 2005 Mar-Apr;58(2):208-13. |
[Wound treatment:
scientific production analysis published in the Revista Brasileira de Enfermagem
from 1970-2003]
[Article in Portuguese]
Pereira
AL, Bachion
MM.
Aluna do Programa de Pos-Graduacao Mestrado em Enfermagem, da Faculdade de
Enfermagem da Universidade Federal de Goias. ginha.ange@bol.com.br
This systematic review aimed to analyze the scientific production concerning
the use of products in the treatment of wounds, published by REBEn from 1970
to 2003. We consulted all numbers of the journal published in the period,
identifying 41 articles of interest. After an appraisal reading we included
11 papers in the sample. We identified a larger publication in the decade
of 1990, prevailing authors of the attendance area, almost-experimental plan
and experience repor. The studied products were papain, propolis, sugar,
| 2: Int J Antimicrob Agents. 2005 Nov;26(5):343-56. |
Antimicrobial activity
of flavonoids.
Cushnie
TP, Lamb
AJ.
Flavonoids are ubiquitous in photosynthesising cells and are commonly found
in fruit, vegetables, nuts, seeds, stems, flowers, tea, wine, propolis and
honey. For centuries, preparations containing these compounds as the principal
physiologically active constituents have been used to treat human diseases.
Increasingly, this class of natural products is becoming the subject of anti-infective
research, and many groups have isolated and identified the structures of flavonoids
possessing antifungal, antiviral and antibacterial activity. Moreover, several
groups have demonstrated synergy between active flavonoids as well as between
flavonoids and existing chemotherapeutics. Reports of activity in the field
of antibacterial flavonoid research are widely conflicting, probably owing
to inter- and intra-assay variation in susceptibility testing. However, several
high-quality investigations have examined the relationship between flavonoid
structure and antibacterial activity and these are in close agreement. In
addition, numerous research groups have sought to elucidate the antibacterial
mechanisms of action of selected flavonoids. The activity of quercetin, for
example, has been at least partially attributed to inhibition of DNA gyrase.
It has also been proposed that sophoraflavone G and (-)-epigallocatechin gallate
inhibit cytoplasmic membrane function, and that licochalcones A and C inhibit
energy metabolism. Other flavonoids whose mechanisms of action have been investigated
include robinetin, myricetin, apigenin, rutin, galangin, 2,4,2'-trihydroxy-5'-methylchalcone
and lonchocarpol A. These compounds represent novel leads, and future studies
may allow the development of a pharmacologically acceptable antimicrobial
agent or class of agents.
Publication Types:
· Review
PMID: 16323269 [PubMed - indexed for MEDLINE]
| 3: Am J Kidney Dis. 2005 Dec;46(6):e125-9. |
Acute renal
failure induced by a Brazilian variety of propolis.
Li YJ, Lin
JL, Yang
CW, Yu CC.
Department of Nephrology, Chang Gung Memorial Hospital, Taipei, Taiwan.
Propolis is a resinous substance collected by honeybees and used in hive construction
and maintenance. Cumulative evidence suggests that propolis may have anti-inflammatory,
antibiotic, antioxidant, antihepatotoxic, and antitumor properties. In addition
to topical applications, products containing propolis have been used increasingly
as dietary supplements. Although reports of allergic reactions are not uncommon,
propolis is reputed to be relatively nontoxic. Its systemic toxicity is rarely
reported and hence may be underestimated. This is the first report of propolis-induced
acute renal failure. A 59-year-old man required hemodialysis for acute renal
failure. The patient had cholangiocarcinoma and had ingested propolis for
2 weeks before presentation. Renal function improved after propolis withdrawal,
deteriorated again after reexposure, and then returned to a normal level after
the second propolis withdrawal. This case indicates that propolis can induce
acute renal failure and emphasizes the need for vigilance and care when propolis
is used as a medicine or dietary supplement.
Publication Types:
PMID: 16310564 [PubMed - indexed for MEDLINE]
| 4: J Agric Food Chem. 2005 Nov 16;53(23):8957-62. |
Evaluation
of the cytotoxicity, genotoxicity, mutagenicity, and antimutagenicity of propolis
from Tucuman, Argentina.
Nieva Moreno MI,
Zampini IC, Ordonez RM, Jaime GS, Vattuone MA,
Isla MI.
Instituto de Estudios Vegetales Dr Antonio Rodolfo Sampietro, Facultad de
Bioquimica, Quimica y Farmacia, Universidad Nacional de Tucuman, Ayacucho
461, 4000 San Miguel de Tucuman, Argentina.
This study evaluates the toxic,
genotoxic/mutagenic, and antimutagenic effects of propolis extract from Amaicha
del Valle,
| 5: Mem Inst Oswaldo Cruz. 2005 Aug;100(5):563-6. Epub 2005 Sep 15. |
Propolis:
anti-Staphylococcus aureus activity and synergism with antimicrobial drugs.
Fernandes Junior A,
Balestrin EC,
Betoni JE, Orsi Rde O, da Cunha Mde L,
Montelli AC.
Departamento de Microbiologia e Imunologia, Instituto de Biociencias, Universidade
Estadual Paulista Julio de Mesquita Filho, Unesp, Botucatu, SP, Brazil. ary@ibb.unesp.br
Propolis is a natural resinous substance collected by bees from tree exudates
and secretions. Its antimicrobial
activity has been investigated and inhibitory action on Staphylococcus aureus
growth was evaluated. The in vitro synergism between ethanolic extract of
propolis (EEP) and antimicrobial drugs by two susceptibility tests (Kirby
and Bauer and E-Test) on 25 S. aureus strains was evaluated. Petri dishes
with sub-inhibitory concentrations of EEP were incubated with 13 drugs using
Kirby and Bauer method and synergism between EEP and five drugs [choramphenicol
(CLO), gentamicin (GEN), netilmicin (NET), tetracycline (TET), and vancomycin
(VAN)] was observed. Nine drugs were assayed by the E-test method and five
of them exhibited a synergism [CLO, GEN, NET, TET, and clindamycin (CLI)].
The results demonstrated the synergism between EEP and antimicrobial drugs,
especially those agents that interfere on bacterial protein synthesis.
PMID: 16184236 [PubMed - indexed for MEDLINE]
| 6: J Ethnopharmacol. 2005 Oct 3;101(1-3):243-8. |
Detection
of galangin-induced cytoplasmic membrane damage in Staphylococcus aureus by
measuring potassium loss.
Cushnie
TP, Lamb
AJ.
Galangin is one of the active antimicrobial principles of propolis or 'bee
glue' and Helichrysum aureonitens, a perennial herb used by South African
indigenes to treat infection. The effect of this compound and antibacterial
agents with known mechanisms of action upon the cytoplasmic membrane integrity
of Staphylococcus aureus was investigated by comparing potassium loss profiles
from bacterial cell suspensions. Using an agar dilution assay, the minimum
inhibitory concentrations (MICs) of the flavonol galangin, the bacteriostatic
antibiotic novobiocin and the bactericidal antibiotic penicillin G against
Staphylococcus aureus NCTC 6571 were determined as being 50 microg/mL, 62.5
ng/mL and 31.3 ng/mL, respectively. When 5x10(7)cfu/mL Staphylococcus aureus
were suspended in 'potassium-free' media containing 50 microg/mL galangin,
a 60-fold decrease in viability was observed after 12 h. Populations of 1x10(9)
cfu/mL Staphylococcus aureus incubated for 12 h in 50 microg/mL galangin lost
21% more potassium than untreated control populations. Novobiocin had no effect
on potassium loss, but populations incubated in 31.3 ng/mL penicillin G exhibited
a 6% increase in potassium loss. This data clearly demonstrates that galangin
causes a significant increase in potassium loss from Staphylococcus aureus
cells, which may be attributed to either direct damage to the cytoplasmic
membrane or indirect damage effected through autolysis/weakening of the cell
wall and consequent osmotic lysis.
| 7: Phytother Res. 2005 Mar;19(3):198-202. |
Antibacterial
effect of plant extracts against Helicobacter pylori.
Nostro A, Cellini L, Di Bartolomeo S,
Di Campli E,
Grande R, Cannatelli MA,
Marzio L, Alonzo V.
Pharmaco-Biological Department,
University of Messina, Messina, Italy.
The aim of this work was to evaluate the antibacterial effect of plant extracts
as alternative and[sol ]or as active agents supporting antibiotics for treating
Helicobacter pylori infection. The effect of either, ethanolic or aqueous
extracts from 17 plant materials were studied against one H. pylori standard
strain and 11 clinical isolates using a disc diffusion test and by evaluating
the minimum inhibitory concentration (MIC) on solid media. An inhibitory activity
against H. pylori strains was recorded in a large percentage of tested plants.
MIC values of ethanolic extracts were from two to four concentration steps
lower than the aqueous ones. In particular, ethanolic extracts of Cuminum
cyminum L. and Propolis expressed MIC90 values of 0.075 mg/mL. The results
show a significant in vitro effect of plant extracts against H. pylori that
could be considered a valuable support in the treatment of the infection and
may contribute to the development of new and safe agents for inclusion in
anti-H. pylori regimens. Copyright 2005 John Wiley & Sons, Ltd.
PMID: 15934015 [PubMed - indexed for MEDLINE]
| 8: Int J Gynaecol Obstet. 2005 May;89(2):127-32. |
Propolis
solution for the treatment of chronic vaginitis.
Imhof M, Lipovac M, Kurz Ch, Barta J, Verhoeven HC,
Huber JC.
Department of Obstetrics and
Gynecology, AKH Vienna, University of Vienna, Vienna, Austria. martin.imhof@akh.ac.at
OBJECTIVE: To evaluate the efficacy of 5% propolis solution in recurrent vaginitis.
METHOD: Fifty-four patients with recurrent vaginal infections having undergone
at least one cycle of antibiotic treatment were instructed to apply a 5% aqueous
propolis solution as a vaginal douche for seven days. Vaginal smears and specific
symptoms were evaluated at baseline and 14 days after treatment. Long-term
well-being was assessed by telephone interview six months after follow-up.
RESULT: At the follow-up, the vaginal smears of 41 patients (75.9%) had improved.
Forty-seven patients (87%) reported reliefs concerning at least one complaint.
Associated improvement of smear and well-being was observed in 36 women (66.7%).
After 6 months, 33 patients (61.1%) were satisfied with their condition without
having undergone further treatment. CONCLUSION: Propolis may have a role as
an alternative treatment for chronic vaginal infection.
Publication Types:
PMID: 15847875 [PubMed - indexed for MEDLINE]
| 9: Phytomedicine. 2005 Mar;12(3):221-8. |
Antibacterial activity
of Turkish propolis and its qualitative and quantitative chemical composition.
Popova
M, Silici
S, Kaftanoglu
O, Bankova
V.
The antibacterial activity of propolis from different regions of
| 10: Contact Dermatitis. 2005 Feb;52(2):96-101. |
Rosacea and
contact allergy to cosmetics and topical medicaments--retrospective analysis
of multicentre surveillance data 1995-2002.
Jappe
U, Schnuch
A, Uter
W.
Department of Dermatology, University of Heidelberg, Heidelberg, Germany.
uta_jappe@med.uni-heidelberg.de
The role of contact allergy in rosacea has rarely been investigated. In this
retrospective study, 361 out of 76,697 patients tested and documented by the
Information Network of Departments of Dermatology between 1995 and 2002 had
rosacea. Patch tests included standard series and constituents of cosmetics
and topical medicaments. 118/361 had additionally been patch tested with their
own cosmetics/medicaments. Positive reactions occurred to nickel (II) sulfate
in 9.3%, fragrance mix in 8.8%, thimerosal in 6.9%, Myroxylon pereirae resin
in 5.9%, potassium dichromate in 4.6% and propolis in 2.8%. Whereas rosacea
patients had a significantly higher risk of contact allergy to propolis compared
to the remaining patients, in an age- and sex-adjusted analysis, contact allergy
to nickel was significantly less frequent in this group. For Lyral, the risk
was elevated, albeit not significantly. Only 2/329 patients were positive
to neomycin sulfate and 1/100 to gentamicin sulfate, among the panel of (topical)
antibiotics tested. Among 118 patients tested with their own products, 3 were
tested to metronidazole, 1 reacting positively. Irritant or doubtful patch
test reactions were provoked by various substances (vehicles, oxidants and
preservatives of various creams), which might also be clinically important,
considering the heightened sensitivity of rosaceous skin.
Publication Types:
PMID: 15725288 [PubMed - indexed for MEDLINE]
| 11: J Agric Food Chem. 2005 Feb 23;53(4):1166-72. |
Some chemical
composition and biological activity of northern Argentine propolis.
Isla MI, Paredes-Guzman JF,
Nieva-Moreno MI,
Koo H, Park YK.
Department of Food Science, College
of Food Engineering, State University of Campinas, P.O. Box 6177, 13083-970,
Campinas, Sao Paulo, Brazil.
Twenty-five samples of propolis were collected from seven different regions
in northern
PMID: 15713035 [PubMed - indexed for MEDLINE]
| 12: Fitoterapia. 2004 Dec;75(7-8):683-9. |
New polyisoprenylated
benzophenones from Venezuelan propolis.
Trusheva B, Popova M, Naydenski H,
Tsvetkova I,
Gregorio Rodriguez J,
Bankova V.
Two new polyisoprenylated benzophenones, 18-ethyloxy-17-hydroxy-17,18-dihydroscrobiculatone
A and 18-ethyloxy-17-hydroxy-17,18-dihydroscrobiculatone B, together with
the known scrobiculatones A and B, were isolated from Venezuelan propolis.
The scrobiculatones A and B showed significant antibacterial activity and
moderate toxicity to Artemia salina nauplii.
PMID: 15567244 [PubMed - indexed for MEDLINE]
| 13: FEMS Microbiol Lett. 2004 Nov 1;240(1):111-6. |
Galangin
expresses bactericidal activity against multiple-resistant bacteria: MRSA,
Enterococcus spp. and Pseudomonas aeruginosa.
Pepeljnjak
S, Kosalec
I.
The antimicrobial activity of three propolis ethanol extracts (EEP) was examined
for various Gram-negative and Gram-positive bacterial species, including multiple-resistant
Staphylococcus aureus, Enterococcus spp. and Pseudomonas aeruginosa strains.
EEP had a good bactericidal activity against Gram-positive species, and all
multiple-resistant bacterial strains tested were sensitive to EEP. Minimal
inhibitory concentrations (MICs) were lower in samples of higher flavonoid
content (from 0.65 to 7.81 mg mL(-1)), indicating the influence of the concentration
of some potent bactericidal compound(s) in propolis or synergism among some
bactericidal compounds. Antimicrobial-guided separation of flavonoid aglycones
(bioassay in situ on thin-layer chromatogram) showed that galangin (3,5,7-trihydroxyflavone)
is one compound in EEP with bactericidal activity. Galangin was isolated by
preparative chromatography. After determining the quantity present, the MIC
against multiple-resistant bacteria was determined. The MIC of galangin against
multiple-resistant bacterial strains was significantly lower (from 0.16 to
0.44 mg mL(-1), p < 0.05) than that of EEP. The bactericidal activity of
galangin against P. aeruginosa strains was present at 0.17+/-0.05 mg mL(-1).
| 14: Pesqui Odontol Bras. 2004 Apr-Jun;18(2):174-9. Epub 2004 Aug 5. |
Natural medicaments
in endodontics -- a comparative study of the anti-inflammatory action.
Silva
FB, Almeida
JM, Sousa
SM.
Center of Biological Sciences and Professions of Health, University of Sacred
Heart, Bauru.
The objective of this study was to evaluate the irritant potential of propolis,
Casearia sylvestris, Otosporin and saline solution (control). Twenty-eight
male Wistar rats were selected, anesthetized and four experimental sites were
designed on their backs. Injections of 2% Evans blue were intravenously administered
in the lateral caudal vein and 0.1 ml of the tested solutions was injected
intradermally into the experimental sites. The animals were killed 1/2, 1,
3 and 6 hours after the injection of the solutions. Each piece of skin containing
the lesion was immersed in formamide and incubated at 45 masculine C for 72
h. After filtration, optical density was measured in a spectrophotometer.
Data were statistically analyzed by a 2-way non-parametric test. The highest
values of extracted dye were observed at 3 hours characterizing a peak in
the inflammatory process. Propolis was the least irritant solution. The natural
medicaments tested in this study may be a valuable alternative for endodontic
treatment.
Publication Types:
PMID: 15311323 [PubMed - indexed for MEDLINE]
| 15: Pharmacol Res. 2004 Mar;49(3):287-92. |
Effect of
water extract of Turkish propolis on tuberculosis infection in guinea-pigs.
Yildirim Z, Hacievliyagil S,
Kutlu NO, Aydin NE, Kurkcuoglu M,
Iraz M, Durmaz R.
Department of Pulmonary Medicine,
University of Inonu School of Medicine, Turgut Ozal Medical Centre, Kampus,
44069, Malatya, Turkey. zyildirim@inonu.edu.tr
Mycobacterium tuberculosis (H(37)R(v))-infected guinea-pig model was used
to investigate the effect of water extract of propolis (WEP). After subcutaneous
inoculation of tubercle bacilli, each animal received oral WEP (n=9), isoniazid
(n=5) or saline (n=6) as placebo and were sacrificed 30 days later. Formation
of necrosis was less prominent in the group treated with WEP, but was not
statistically significant (P>0.05). The granuloma formation in the same
group was more prominent than the placebo and isoniazid groups; however, this
finding failed to reach statistical significance by the Kruskal-Wallis test
(P>0.05). These findings suggest that Turkish WEP may have a limited effect
on the development of tuberculosis infection in this guinea-pig model.
PMID: 14726226 [PubMed - indexed for MEDLINE]
| 16: Microbiol Res. 2003;158(4):353-7. |
In vitro antimicrobial
activity of propolis and synergism between propolis and antimicrobial drugs.
Stepanovic
S, Antic
N, Dakic
I, Svabic-Vlahovic
M.
Department of Bacteriology, Institute of Microbiology and Immunology, School
of Medicine, University of Belgrade, Dr Subotica 1, 11000 Belgrade, Serbia.
stepan@afrodita.rcub.bg.ac.yu
The aim of this study was to investigate antimicrobial properties of ethanolic
extract of 13 propolis (EEP) samples from different regions of Serbia against
39 microorganisms (14 resistant or multiresistant to antibiotics), and to
determine synergistic activity between antimicrobials and propolis. Antimicrobial
activity of propolis samples was evaluated by agar diffusion and agar dilution
method. The synergistic action of propolis with antimicrobial drugs was assayed
by the disc diffusion method on agar containing subinhibitory concentrations
of propolis. Obtained results indicate that EEP, irrespectively of microbial
resistance to antibiotics, showed significant antimicrobial activities against
Gram-positive bacteria (MIC 0.078%-1.25% of EEP) and yeasts (0.16%-1.25%),
while Gram-negative bacteria were less susceptible (1.25%-->5%). Enterococcus
faecalis was the most resistant Gram-positive bacterium, Salmonella spp. the
most resistant Gram-negative bacteria, and Candida albicans the most resistant
yeast. EEP showed synergism with selected antibiotics, and displayed ability
to enhance the activities of antifungals. The shown antimicrobial potential
of propolis alone or in combination with certain antibiotics and antifungals
is of potential medical interest.
PMID: 14717457 [PubMed - indexed for MEDLINE]
| 17: Clin Chim Acta. 2003 Dec;338(1-2):11-6. |
Protective
role of Egyptian propolis against tumor in mice.
El-khawaga
OA, Salem
TA, Elshal
MF.
Chemistry Department, Faculty of Science, Mansoura University, Mansoura City,
Egypt. elkhawaga70s@mans.edu.eg
BACKGROUND: Propolis has numerous biologic activities including antibiotic,
antifungal, antiviral and anti-inflammatory properties. The present work is
aimed to study the effect of crude Egyptian propolis on tumor in mice induced
by Ehrlich ascitis carcinoma (EAC) cell line. RESULTS: The administration
of propolis (160 mg/kg body weight), by gastric intubation 2 h before the
intraperitoneal injection of EAC, effectively inhibited tumor growth and the
proliferation of EAC. The tumor volume was markedly reduced from 7+/-0.9 ml
in EAC-infected mice to 1.6+/-0.95 ml in propolis-treated mice. Also, the
lipid peroxide level which was 13.3+/-1.24 nmol malodialdehyde (MDA)/mg protein
in EAC infected mice was significantly decreased to 3.3+/-2.1 nmol MDA/mg
protein. Reduced glutathione (GSH) and glutathione S-transferase (GST) concentrations
were markedly increased in propolis-treated mice. This effect was associated
with inhibition of cell cycle progression and induction of apoptosis. Administration
of propolis 2 h before injection of EAC arrested cells in G0/G1 phase and
resulted in a decrease in the viability, DNA, total RNA and protein level
of tumor cells. CONCLUSIONS: Crude Egyptian propolis has a strong inhibitory
activity against tumors. The anti-tumor mechanism may be mediated by preventing
oxidative damage and induction of apoptosis.
PMID: 14637260 [PubMed - indexed for MEDLINE]
| 18: J Ethnopharmacol. 2003 Oct;88(2-3):189-93. |
Flavonoids
and trypanocidal activity of Bulgarian propolis.
Prytzyk E, Dantas AP, Salomao K, Pereira AS, Bankova VS, De Castro SL,
Neto FR.
Ladetec, Instituto de Quimica, Universidade Federal do Rio de Janeiro, Ilha
do Fundao, Cidade Universitaria, CT Bl. A, 21949-900
Acetone and ethanol extracts of two Bulgarian propolis samples (Bur and Lov)
were investigated by high temperature high resolution gas chromatography coupled
to mass spectrometry (HT-HRGC-MS), and their activity against Trypanosoma
cruzi was evaluated. The ethanol extracts--Et-Bur and Et-Lov--showed similar
composition, with a high content of flavonoids, and strong inhibitory activity
against T. cruzi proliferative epimastigotes, which were more susceptible
than trypomastigotes. In the presence of blood, the activity of Et-Bur or
Et-Lov against trypomastigotes was similar to that of the standard drug, crystal
violet. Both extracts also showed similar and significant activity against
Staphylococcus aureus and Candida albicans, while being inactive against Escherichia
coli. The acetone extract, Ket-Bur, was more active than Et-Bur against both
forms of T. cruzi.
| 19: J Med Microbiol. 2003 May;52(Pt 5):417-9. |
Inhibition
of Helicobacter pylori growth in vitro by Bulgarian propolis: preliminary
report.
Boyanova L, Derejian S, Koumanova R,
Katsarov N, Gergova G, Mitov I, Nikolov R, Krastev Z.
Department of Microbiology, Medical
University of Sofia, Sofia, Bulgaria. l.boyanova@lycos.com
Bee glue (propolis) possesses antimicrobial, anti-inflammatory, anaesthetic
and immunostimulating activities. The aim of the study was to evaluate the
inhibitory effect of Bulgarian propolis on Helicobacter pylori growth in vitro.
Activity of 30% ethanolic extract of propolis (EEP) against 38 clinical isolates
of H. pylori was evaluated by using the agar-well diffusion method. Ethanol
was used as a control. In addition, the effect of propolis on the growth of
26 H. pylori and 18 Campylobacter strains was tested by the disc diffusion
method. Mean diameters of H. pylori growth inhibition by the agar-well diffusion
method, using 30, 60 or 90 microl EEP or 30 microl ethanol per well, were
17.8, 21.2, 28.2 and
| 20: J Ethnopharmacol. 2003 May;86(1):69-73. |
Antimicrobial
activity of propolis samples from two different regions of
Kartal
M, Yildiz
S, Kaya
S, Kurucu
S, Topcu
G.
Department of Pharmacognosy, Faculty of Pharmacy, Ankara University, 06100
Ankara, Turkey. kartal@pharmacy.ankara.edu.tr
Antimicrobial activity of two propolis samples from Kazan and Marmaris regions
in
| 21: Phytother Res. 2003 Mar;17(3):285-9. |
Brazilian
propolis: physicochemical properties, plant origin and antibacterial activity
on periodontopathogens.
Santos FA, Bastos EM, Maia AB, Uzeda M, Carvalho MA,
Farias LM, Moreira ES.
Departamento de Microbiologia,
Universidade Federal de Minas Gerais, Brazil.
Propolis samples collected in the dry and rainy seasons, from an experimental
apiary located in a cerrado vegetation region in
PMID: 12672164 [PubMed - indexed for MEDLINE]
| 22: Pol J Vet Sci. 2002;5(4):223-5. |
Investigation on
the inhibition of Campylobacter jejuni growth with the applications of some
preservatives, medicines, herbs and herb preparations.
Uradzinski
J, Szteyn
J, Kafel
S.
Department of Animal Products Hygiene, Faculty of Veterinary Medicine, University
of Warmia and Mazury, Oczapowskiego 14, 10-719 Olsztyn, Poland. janurad@moskit.uwm.edu.pl
The aim of this study was to determine the influence of chosen preservatives,
medicines, herbs and herb preparations on 39 Campylobacter jejuni strains,
which were isolated from fresh poultry carcasses. De-Nol and ventrisol were
used in the original concentration. Propolis, propolan, artecholin and aukalen
were of pharmacies origin. The rest of substances examined were 10% water
solutions. Out of 11 substances examined, potassium sorbate, sodium benzoate,
De-Nol and ventrisol exerted the strongest inhibitory action on Campylobacter
jejuni.
PMID: 12512554 [PubMed - indexed for MEDLINE]
| 23: Fitoterapia. 2002 Nov;73 Suppl 1:S1-6. |
Propolis,
an old remedy used in modern medicine.
Castaldo
S, Capasso
F.
Department of I.N.P.S. of Naples, via Medina 63, Naples, Italy.
Propolis is one of the few natural remedies that has maintained its popularity
over a long period of time. The pharmacologically active molecules in the
propolis are flavonoids and phenolic acids and their esters. These components
have multiple effects on bacteria, fungi and viruses. In addition, propolis
and its components have anti-inflammatory and immunomodulatory activities.
Moreover, propolis has been shown to lower blood pressure and cholesterol
levels. However, clinical studies to substantiate these claims are required.
Publication Types:
· Review
PMID: 12495704 [PubMed - indexed for MEDLINE]
| 24: Pol J Vet Sci. 2002;5(3):197-202. |
The use of some
immunomodulators and non-antibiotic drugs in a prophylaxis and treatment of
mastitis.
Malinowski
E.
Department of Pathophysiology of Reproduction and Mammary Gland. National
Veterinary Research Institute, Powstancow Wikp, 10, 85-090
Antibiotics are widely used in treatment and prophylaxis of mastitis, but
their antibacterial and therapeutic efficacy continues to decrease. New methods
of prophylaxis of mastitis with the use of vaccines and biological response
modifiers are reviewed. Prophylactic activity of staphylococcal vaccines should
be investigated in the future because of difficulties in successful treatment
of infections caused by these organisms. Vaccination with J5 bacterin (0111:B4)
reduced duration of IMI and local signs of clinical coliform-mastitis. Some
immunomodulators proved to be effective in treatment of mastitis during lactating
period. Promising results were obtained with the use of giseng saponin, herbal
gel, herbal extracts, propolis, lysosubtilin, antibacterial proteins, and
lysozyme dimer especially.
· Review
PMID: 12448082 [PubMed - indexed for MEDLINE]
| 25: Z Naturforsch [C]. 2002 Mar-Apr;57(3-4):395-402. |
Egyptian propolis:
3. Antioxidant, antimicrobial activities and chemical composition of propolis
from reclaimed lands.
Hegazi
AG, Abd
El Hady FK.
Department of Parasitology, National Research Center, Dokki, Giza, Egypt.
ahmedgaffer@mailer.suc.eun.eg
The free radical scavenging effect of two propolis samples collected from
reclaimed land,
| 26: Z Naturforsch [C]. 2002 Mar-Apr;57(3-4):386-94. |
Egyptian propolis:
2. Chemical composition, antiviral and antimicrobial activities of
Abd
El Hady FK, Hegazi
AG.
Department of Chemistry of Natural Products, National Research Center, Dokki,
Giza, Egypt.
Three propolis samples from East Nile Delta,